Generic Alprazolam (Xanax) 0.5mg Tablets
Pack of 60 tablets · Tablets
Standard-strength alprazolam for short-term relief of severe situational anxiety, where the lower 0.25mg dose is not sufficient. Not licensed in the UK.
Controlled drug — important information
This medicine is a controlled drug under the UK Misuse of Drugs Regulations. It is supplied in limited quantities, only after a full clinical assessment, and may not be carried abroad without the right paperwork (a personal export licence is required for trips of 3 months or more). Misuse can cause serious harm and dependence, and is a criminal offence.
GP information & consent
For all Prescription Only Medicines — and particularly controlled drugs — the clinic requires your GP details. In line with healthcare regulations, we will notify your GP when supplying high-risk Prescription Only Medicines such as controlled drugs. You can opt out of this consent, however this may affect the prescriber's decision to prescribe certain medications.
To support our safety checks, we may also request access to your GP medical records. This is an optional consent, however declining may impact the prescriber's ability or decision to prescribe.
Only one controlled-drug medication per basket.
Request consultationOfficial medicine information
View the SmPC and Patient Information Leaflet on emc
electronic Medicines Compendium — the authoritative source for UK licensed medicine information.
Active ingredient
Alprazolam
Strength
0.5mg (500 micrograms)
Form
Tablets
Pack size
Pack of 60 tablets
How it works
Same active ingredient as the 0.25mg tablet, at a higher dose. Provides a stronger short-acting calming effect on the nervous system for severe anxiety symptoms.
How to take
Adults: usually 0.5mg taken as needed for short, defined periods, or as directed. Strictly short-term use under pharmacist supervision.
Possible side effects
- Drowsiness or sedation
- Light-headedness or unsteadiness, especially in older adults
- Reduced concentration or memory
- Muscle weakness
- Less commonly: low mood, confusion or paradoxical agitation
Important warnings
- Risk of dependence and tolerance — only used short term (typically a few days, up to 2–4 weeks including tapering).
- Do not drive or operate machinery if you feel drowsy or impaired.
- Do not combine with alcohol or other sedating medicines (including opioids) — serious breathing problems can occur.
- Not suitable in severe breathing problems, sleep apnoea, severe liver disease or myasthenia gravis.
- Not for use in pregnancy or breastfeeding unless specifically advised.
- Stopping suddenly after regular use can cause withdrawal — always follow the pharmacist's tapering plan.
- Alprazolam is not licensed in the UK — it is only supplied on a private, named-patient basis after careful pharmacist assessment.
- Higher dependence potential than longer-acting benzodiazepines — only used when clinically justified.
Storage
Store below 25°C in the original packaging. Keep out of the sight and reach of children.
How this medicine is supplied
Safer supply for high-risk medicines
- Identity verification before any supply is approved.
- GP notification — and, where appropriate, verification with your GP.
- Direct prescriber contact by phone or short video where clinically indicated — not questionnaire only.
- Limited quantities and structured review.
- Signed-for adult delivery only — the patient must be present at the address.
Your prescriber
Pharmacist Independent Prescriber
All Prescription Only Medicines on this page are reviewed and (where appropriate) prescribed by a GPhC-registered Pharmacist Independent Prescriber. You will be told your prescriber's name and GPhC registration number before treatment is supplied.
Lead Prescriber for this clinic: Jane Doe MRPharmS, IP — GPhC Reg. 2000000. Verify on the GPhC pharmacist register.
Important
This information is provided for general guidance only and is not a substitute for professional clinical advice. Treatment is only supplied following a consultation, suitability checks and pharmacist review. If this medicine is not suitable for you, our pharmacist will discuss alternatives.
Always read the patient information leaflet supplied with your medicine. If you have a medical emergency, call 999 immediately.
Suspected side effects can be reported via the MHRA Yellow Card scheme. Reporting helps make medicines safer for everyone.
Last reviewed by our Superintendent Pharmacist: Jane Doe MRPharmS, April 2026.
Take the next step toward better sleep, less stress, and better pain support.
Browse our treatments — you can request a confidential, pharmacy-led consultation.
Treatment available where clinically appropriate.