Naproxen 500mg Tablets
Pack of 56 tablets · Gastro-resistant tablets
Higher-strength NSAID for moderate pain and inflammation, including musculoskeletal conditions and acute flare-ups.
GP information & consent
For all Prescription Only Medicines — and particularly controlled drugs — the clinic requires your GP details. In line with healthcare regulations, we will notify your GP when supplying high-risk Prescription Only Medicines such as controlled drugs. You can opt out of this consent, however this may affect the prescriber's decision to prescribe certain medications.
To support our safety checks, we may also request access to your GP medical records. This is an optional consent, however declining may impact the prescriber's ability or decision to prescribe.
Official medicine information
View the SmPC and Patient Information Leaflet on emc
electronic Medicines Compendium — the authoritative source for UK licensed medicine information.
Active ingredient
Naproxen
Strength
500mg
Form
Gastro-resistant tablets
Pack size
Pack of 56 tablets
How it works
Provides a stronger anti-inflammatory and pain-relieving effect than the 250mg strength, by blocking prostaglandin production. Used for moderate pain, inflammatory joint conditions or short-term flare-ups.
How to take
Adults: usually one tablet (500mg) twice a day with or after food, or as directed. Take with a full glass of water. Pharmacist may recommend stomach protection alongside.
Possible side effects
- Indigestion, stomach pain or nausea
- Headache or dizziness
- Diarrhoea or constipation
- Less commonly: stomach ulcers, raised blood pressure or kidney effects
Important warnings
- Take with food to reduce stomach upset.
- Not suitable if you have a history of stomach ulcers, severe heart, kidney or liver disease.
- Avoid in the third trimester of pregnancy; speak to a pharmacist if pregnant, planning pregnancy or breastfeeding.
- Tell your pharmacist if you take blood thinners, steroids, SSRIs or other NSAIDs.
- Stomach protection (e.g. omeprazole) is often recommended at this strength.
Storage
Store below 25°C in the original packaging. Keep out of the sight and reach of children.
How this medicine is supplied
Safer supply for high-risk medicines
- Identity verification before any supply is approved.
- GP notification — and, where appropriate, verification with your GP.
- Direct prescriber contact by phone or short video where clinically indicated — not questionnaire only.
- Limited quantities and structured review.
Your prescriber
Pharmacist Independent Prescriber
All Prescription Only Medicines on this page are reviewed and (where appropriate) prescribed by a GPhC-registered Pharmacist Independent Prescriber. You will be told your prescriber's name and GPhC registration number before treatment is supplied.
Lead Prescriber for this clinic: Jane Doe MRPharmS, IP — GPhC Reg. 2000000. Verify on the GPhC pharmacist register.
Important
This information is provided for general guidance only and is not a substitute for professional clinical advice. Treatment is only supplied following a consultation, suitability checks and pharmacist review. If this medicine is not suitable for you, our pharmacist will discuss alternatives.
Always read the patient information leaflet supplied with your medicine. If you have a medical emergency, call 999 immediately.
Suspected side effects can be reported via the MHRA Yellow Card scheme. Reporting helps make medicines safer for everyone.
Last reviewed by our Superintendent Pharmacist: Jane Doe MRPharmS, April 2026.
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